Pharmaceutical sciences
Yoga Windhu Wardhana; Bayu Indradi; Ade Zuhrotun; Rini Hendriani; Winda Agnestia Maranna Saragih; Savira Ekawardhani; Hesti Lina Wiraswasti; Enny Rohmawaty; Sumartini Dewi
Abstract
In this study, thermal stability and pH for the antioxidant activity of the ethanol extract of ciplukan (Physalis angulata Linn) herbs had been studied. Among the antioxidant activity methods, the use of DPPH (2,2-diphenyl-1-picrylhydrazyl) reagent is simple and easy to use. The thermal effect was observed ...
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In this study, thermal stability and pH for the antioxidant activity of the ethanol extract of ciplukan (Physalis angulata Linn) herbs had been studied. Among the antioxidant activity methods, the use of DPPH (2,2-diphenyl-1-picrylhydrazyl) reagent is simple and easy to use. The thermal effect was observed by warming the sample at 50, 70, and 100 °C in intervals of 30, 45, and 60 min. The results showed that the half-maximal Inhibitory Concentration (IC50) of the extract was 185.53+1.35, which was classified as medium. Based on these results, a significant decrease was observed at 100 °C and pH=8. Thus, the pKa of the extract is recommended for maintaining stability at a pKa value of 3.83, which is proven to maintain a spot in the pH range of 4.
